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Wednesday, June 4, 2025

Creatine vs. creatinine

 
Creatine and creatinine are related but distinct substances in the body. 
 
Creatine is a compound used for energy production, particularly in muscle cells, while creatinine is a waste product of creatine metabolism. Essentially, creatine is the precursor, and creatinine is the byproduct. 

Imagine creatine as a fuel source for your muscles. When that fuel is used, a byproduct (creatinine) is created, which your kidneys then filter out of your bloodstream. 
 
 
Creatine

Function:

  • Primarily used for replenishing ATP (adenosine triphosphate), the body's main energy currency, especially during short bursts of intense activity. 
Formation:
  • Synthesized in the liver, kidneys, and pancreas, and also obtained through protein-rich foods like meat and fish. 
Storage:
  • Stored in skeletal muscle as phosphocreatine. 
Use:
  • Taken as a supplement to enhance athletic performance, muscle strength, and recovery. 


Creatinine

  • Function: A waste product generated from the breakdown of creatine. 
  • Formation: Creatinine is formed in muscles when creatine breaks down. 
  • Excretion: Filtered by the kidneys and excreted in urine. 
  • Medical Relevance: Blood creatinine levels are used as an indicator of kidney function, with elevated levels potentially suggesting impaired kidney filtration. 


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